Microbial contamination and labelling of self-prepared, multi-dose phenylephrine solutions used at a teaching hospital

Authors

  • Andreas van den Heever University of the Witwatersrand
  • Juan Scribante University of the Witwatersrand
  • Helen Perrie University of the Witwatersrand
  • Warren Lowman Vermaak and Partners Pathologists

Keywords:

contamination, microbial, multi-dose, phenylephrine, self-prepared solutions

Abstract

Background: Common practice at Chris Hani Baragwanath Academic Hospital (CHBAH) is to use boluses from a self-prepared, multi-dose phenylephrine solution to treat spinal anaesthesia-induced hypotension in patients undergoing a Caesarean section. The aims of this study were to determine if there was microbial contamination of the solutions and to evaluate whether healthcare workers adhered to appropriate labelling and aspiration practices. Methods: A sample was collected and the labelling data were documented from the solutions found in the two obstetric theatres at CHBAH over a three-month period. The samples were sent to a laboratory for microbial investigation. Results: Microbial contamination was identified in 6.4% of samples collected. The name of the solution was indicated on 100% of the containers and the concentration of the solution was on 96.4%. The date the solution was prepared was indicated on 74.6% of containers and the time the solution was prepared was on 57.3%. Only 8.2% of healthcare workers who prepared the solution confirmed it by placing a signature on the container. Labelling data were written directly on 100% of the containers and a spike-device was used in 64.5% of the containers. Conclusions: This study demonstrated microbial contamination of the solution and may indicate an infection hazard. Healthcare workers also did not adhere to appropriate labelling and aspiration practices. This is important for all patients from a patient safety perspective and the need to improve quality of care. (Full text available online at www.medpharm.tandfonline.com/ojaa) South Afr J Anaesth Analg 2016; DOI: 10.1080/22201181.2016.1251062

Author Biographies

Andreas van den Heever, University of the Witwatersrand

School of Clinical Medicine Department of Anaesthesiology Faculty of Health Sciences University of the Witwatersrand

Juan Scribante, University of the Witwatersrand

School of Clinical Medicine Department of Anaesthesiology Faculty of Health Sciences University of the Witwatersrand

Helen Perrie, University of the Witwatersrand

School of Clinical Medicine Department of Anaesthesiology Faculty of Health Sciences University of the Witwatersrand

Warren Lowman, Vermaak and Partners Pathologists

Vermaak and Partners Pathologists Pretoria; and Wits Donald Gordon Medical Centre Johannesburg; and Wits School of Pathology Faculty of Health Sciences University of the Witwatersrand

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Published

2016-11-30

Issue

Section

Research Articles